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PHA 5127
Basic Principles of Dose Optimization I
Lecture Schedule Fall 2000
Wednesday 3th Period MSB Auditorium
Friday 5th Period C1-11
Input |
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| Aug. 23 | Introduction | 1-3 |
| Aug. 25 | Basic Pharmacokinetics (incl. first-order, zero order processes) | 4-6 |
| Aug. 30 | Volume of Distribution, Clearance, | 6,7 |
| Sept. 1 | Volume of Distribution, Clearance, | |
| Sept. 6 | Case Study I Homework Set I |
|
| Sept. 8 | Half-Life, Bioavailability | Sections of 9-13 |
| Sept. 13 | Protein Binding- Tissue Distribution-Volume of distribution | 32, 33,34 |
| Sept. 15 | Metabolism (High and Low Extraction Drugs, Intrinsic clearance) | 35,36, 37 |
| Sept. 20 | Metabolism (Induction and Inhibition) | 38 |
| Sept. 22 | Renal Excretion | 40 |
| Sept. 27 | Case Study II Homework Set II |
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| Sept. 29 | Renal Excretion- Non-Renal Excretion | 40, 41 |
| Oct. 4 | One compartment Body Model | 9-13 |
| Oct. 6 | One compartment Body Model | 9-13 |
| Oct. 11 | Case Study III Homework Set III |
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| Oct. 13 | Single IV Bolus | 9-13 |
| Oct. 18 | Multiple IV Bolus | 14, 15, 16, 17, 18, 19 |
| Oct. 20 | Multiple IV Bolus | 14, 15, 16, 17, 18, 19 |
| Oct. 25 | Case Study IV Homework Set IV |
|
| Oct. 27 | First Exam | |
| Nov. 1 | Single Oral Dose | 28-31 |
| Nov. 3 | Multiple Oral Dose | |
| Nov. 8 | IV Continuous Infusion | 21,22,23 |
| Nov. 10 | Veterans Day No Class (Homecoming) | |
| Nov. 15 | Multiple IV Short Term Infusion | 24 |
| Nov. 17 | Case Study V Homework IV |
|
| Nov. 22 | Two compartment Body Model | 25-27 |
| Nov. 24 | Thanksgiving Holiday No Class | |
| Nov. 29 | Three Compartment Body Model | |
| Dec. 1 | Nonlinear Pharmacokinetics | 39, 40 |
| Dec. 6 | Evaluation and Case Study VI | |
| Final Exam |