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Basic Principles of Dose Optimization I
Lecture Schedule Fall 2001
Tues 6th Period, 12:50-1:40; H6-11(6120)
Thurs. 6th Period, 11:45-12:35; H6-11(6120)
Last modified 08/01/01
| Aug. 23 | Introduction | 1-3 |
| Aug 28 | Basic Pharmacokinetics (incl. first-order, zero order processes) | 4-6 |
| Aug. 33 | Volume of Distribution, Clearance | 6,7 |
| Sept. 4 | Volume of Distribution | |
| Sept. 6 | Case Study I Homework Set I |
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| Sept. 11 | Clearance | Sections of 9-13 |
| Sept. 13 | Half-Life, Bioavailability | 32,33,34 |
| Sept. 18 | Protein Binding-Tissue Distribution-Volume of Distribution | 35,36,37 |
| Sept. 20 | Metabolism (High and Low Extraction Drugs, Intrinsic Clearance) | |
| Sept. 25 | Metabolism (Induction and Inhibition) | 40 |
| Sept. 27 | Case Study II Homework Set II |
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| Oct. 2 | Renal Excretion | 40, 41 |
| Oct. 4 | Renal Excretion-Non-Renal Excretion | |
| Oct. 9 | One Compartment Body Model | 9-13 |
| Oct. 11 | Case Study III Homework Set III |
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| Oct. 16 | One Compartment Body Model | 9-13 |
| Oct 18 | Case Study IV Homework Set IV |
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| Oct. 23 | Single IV Bolus | 14, 15, 16, 17, 18, 19 |
| Oct. 25 | FIRST EXAM (C1-15;C1-17) NOTE ROOM CHANGE |
| Oct. 30 | Multiple IV Bolus | 28-31 |
| Nov. 1 | Multiple IV Bolus | |
| Nov. 6 | Single Oral Dose | 21, 22, 23 |
| Nov. 8 | Multiple Oral Dose | |
| Nov. 13 | IV Continuous Infusion | 24 |
| Nov. 15 | Case Study V Homework Set V |
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| Nov. 20 | Multiple IV Short Term Infusion | 25-27 |
| Nov. 22 | THANKSGIVING HOLIDAY NO CLASS | |
| Nov. 27 | Two Compartment Body Model | |
| Nov. 29 | Three Compartment Body Model | 39, 40 |
| Dec. 4 | Nonlinear Pharmacokinetics | |
| Dec. 6 | Evaluation and Case Study VI | |
| FINAL EXAM |