RESEARCH INTERESTS

• Physiology of pregnancy
• Corticosteroid effects on fluid balance and control of blood pressure
• Corticosteroid effects on the brain
• Progesterone antagonism of  mineralocorticoid action

• Corticosteroid receptor (MR and GR) binding
• Western blot analysis of proteins
• Real –time PCR analysis of steroid target genes

• Feedback control of ACTH
• Corticosteroid action in pregnancy
• Animal models of hypoadrenocorticism

1. Keller-Wood M., Wood C.E.  “Pituitary-adrenal Physiology During Pregnancy.”  The Endocrinologist, 11:159-170 (2001).
2. Keller-Wood M., Cudd T.A., Norman W., Caldwell S.M., Wood C.E.  “A Model in Sheep for the Study of Maternal Adrenal Function During Pregnancy.”  Laboratory Animal Science, 48:507-512 (1998).
3. Roesch D.M., Keller-Wood M.  “Differential Effects of Pregnancy on Mineralocorticoid and Glucocorticoid Receptor Availability and Immunoreactivity in Cortisol Feedback Sites.” Neuroendocrinology, 70:55-62 (1999).
4. Orbach P., Wood C.E., Keller-Wood M.  “Nitric Oxide Reduces Pressor Responsiveness During Ovine Hypoadrenocorticism.”  Clinical Exp. Pharm. Physiol, 28: 459-462 (2001).
5. Keller-Wood M., Wood C.E.  “Pregnancy Alters Cortisol Feedback Inhibition of Stimulated ACTH: Studies in Adrenalectomized Ewes.”  American Journal of Physiology,  280:R1790-8, (2001).