GUENTHER HOCHHAUS, PH.D.

PROFESSOR

DEPARTMENT OF PHARMACEUTICS

RESEARCH INTERESTS

1. Pharmacokinetics/dynamics of Antiasthmatics
2. Drug analysis
3. Peptide Metabolism
4. Mode of action of dymorphins

AREAS OF TECHNICAL EXPERTISE

1. HPLC/175/175
2. RIA
3. Receptor binding

RESEARCH EXPERTISE

Telephone: (352) 273-7861
Fax: (352) 273-7854
E-mail: hochhaus@cop.ufl.edu

SAMPLE PUBLICATIONS

What pharmacokinetic and pharmacodynamic properties are important for inhaled glucocorticoids? G. Hochhaus. Annals of Allergy, Asthma, & Immunology 98, S7-S15 (2007)

Pharmacokinetic/Pharmacodynamic Profile of Mometasone Furoate Nasal Spray: Potential Effects on Clinical Safety and Efficacy. G. Hochhaus. Clin. Therapeutics 30, 98-107 (2008) .

Laser-ablated nanofunctional polymers for the formulation of slow-release powders for dry powder inhalers: physicochemical characterization and slow-release characteristics . I. Coowanitwong, G. Patel, W-S Kim, V. Craciun, J. R. Rocca, R. R. Singh, and G. Hochhaus. J Pharmacy Pharmacol. 59, 1473-1484 (2007)

Plasma levels of fluticasone and budesonide following inhalation: effect of bronchoconstriction. K. Mortimer, T.W. Harrison, Y.T. K. Wu, S. Lewis, S. Sahasranaman, G. Hochhaus, A.E. Tattersfield. Br. J. Clin. Pharmacol. 64, 439-444 (2007)

Pharmacokinetic/pharmacodynamic evaluation of urinary cortisol suppression after inhalation of fluticasone propionate and mometasone furoate. Z.R. Tayab, T.C. Fardon, D.K.C. Lee, K. Haggart, L.C. McFarlane, B.J. Lipworth, G. Hochhaus. Br. J. 64, 698-705 (2007)

Pharmacokinetic/pharmacodynamic factors and steroid sensitivity. G. Hochhaus. Steroid Insensitivity. Edited by B. Adcock (in press).