HARTMUT DERENDORF, PH.D.

PROFESSOR

DEPARTMENT OF PHARMACEUTICS

RESEARCH INTERESTS

1. Pharmacokinetics and pharmacodynamics of corticosteroids
2. Pharmacokinetics and pharmacodynamics of analgesics
3. Pharmacokinetics and pharmacodynamics of antibiotics

AREAS OF TECHNICAL EXPERTISE

1. HPLC of drugs and metabolites in biological fluids
2. Computer modeling for PK-PD analysis
3. Somatosensory evoked potencies to measure analgesic effects
4. Microdialysis to measure free tissue concentrations of drugs

CONSULTING EXPERTISE

1. Pharmacokinetics
2. Pharmacodynamics

Telephone (352) 846-2726
Fax (352) 392-3249
E-mail hartmut@cop.ufl.edu

SAMPLE PUBLICATIONS

1. S. Krishnaswami, H. Möllmann, H. Derendorf, G. Hochhaus
   A sensitive LC-MS/MS method for the quantification of fluticasone propionate in human plasma
   J. Pharm. Biomed. Anal. 22, 123-129 (2000).
2. N.V. Nagaraja, Y.J. Park, S. Jeon, C.D. Sands, H. Derendorf
   Population pharmacokinetics of digoxin in Korean patients
   Int. J. Clin. Pharmacol. Ther. 38, 291-297 (2000).
3. G. Hochhaus, J. Barrett, H. Derendorf
   An evolution of pharmacokinetics and pharmacokinetic/dynamic correlations during the 20^th century
   J. Clin. Pharmacol., 40, 908-917(2000).
4. S. Krishnaswami, G. Hochhaus, H. Derendorf
   An interactive algorithm for the assessment of cumulative cortisol suppression during inhaled corticosteroid therapy
   AAPS Pharmsci. (http://www.pharmsci.org) 2(3), article 22 (2000).
5. B. Meibohm, H. Derendorf
   Pharmacokinetics and pharmacodynamics of biotechnological drugs
   In "Pharmazeutische Biotechnologie ", edited by O. Kayser and R.H. Müller Wissenschaftliche Verlagsgesellschaft mbH Stuttgart, pg103-124(2000).