Donna Wielbo Ph.D.
ACADEMIC QUALIFICATIONS
B.Sc. (Honors) in Microbiology, University of Aberdeen, Scotland, 1981-1985.
M.Sc. in Forensic Science, University of Strathclyde, Glasgow, Scotland, 1985-1986.
Ph.D. in Pharmacy, University of Illinois at Chicago, Chicago, USA, 1988-1991.
EMPLOYMENT
December 2003 present. Research Associate Professor, Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL USA.
Responsibilities: To develop and maintain online certificate and MS degree programs in forensic disciplines including forensic toxicology, forensic drug chemistry and forensic serology and DNA. To provide lecture content and materials as necessary for all online programs. Assist in the development and implementation of program policies. Act as liaison between students and UF faculty as well as UF faculty and the UF Division of Distacne and Continuing Education. Instructor for 9 online courses and assists when required in all other courses.
June 2003 November 2003, Acting Director of Training and Education, National Forensic Science Technology Center, Largo, FL. USA
September 2002 June 2003, Deputy Director of Training and Education National Forensic Science Technology Center
November 2002 Dec 2003, Lecturer and Instructor of Record for MS degree in Forensic Serology and DNA, Department of Continuing Education, University of Florida; Adjunct Associate Professor, Department of Medicinal Chemistry, University of Florida
January 2002 September 2002, Deputy Director of Scientific and Technical Services National Forensic Science Technology Center
October 2000 - January 2002, Curriculum Designer - National Forensic Science Technology Center
October 1999 November 2002, Program Coordinator Distance Education in Forensic Science and Toxicology.
Dec 1997- October 1999, Senior Research Scientist, Gene Discovery Group, CuraGen Corporation.
August 1996-Jan 1998, Assistant Professor, Department of Medicinal Chemistry, University of Florida,
July 1994-August 1996, Assistant Professor, Department of Pharmaceutics, University of Florida.
Research Interests
Antisense inhibition of hypertension in rat models of hypertension.
Jan 1993 -June 1994, American Heart Association Post Doctoral Research Associate, Department of Physiology, University of Florida.
May 1992 - Dec. 1992 Research Associate, Department of Pediatrics/Neonatology, University of Illinois at Chicago.
Studies involved the transplacental effects of cocaine and its metabolites on the hemodynamics of the mother and fetus of a baboon animal model
1991-1992 Assistant Director, ACCU-Lab Medical Testing Inc.
Responsibilities: Supervised day to day operations of a forensic drug testing laboratory involving immunoassay and GC-MS procedures.
1988-1991 Teaching Assistant and Doctorate Student, Department of Pharmacodynamics, University of Illinois at Chicago, Chicago, IL.
Principle research area - The Use of Fourier Transform Infrared Spectroscopy in the Analysis of Particulate Matter.
1986 -1988 Scientific Officer, Home Office Forensic Science Laboratory, Huntingdon, England.
Responsibilities: Examination and processing of biological cases involving; blood, semen and trace evidence; Assisted at crime scenes and attended court; taught courses in hair and fiber evidence in relation to sexual offenses to Police officers; supervised Masters research students and carried out research concerning the identification of the enzyme Alpha-Amylase in biological fluids.
PROFESSIONAL MEMBERSHIP
Associate Member of the American Academy of Forensic Sciences Feb 2006
Associate Member of the International Association of Police Chiefs, 2003 present
Member of the Institute of Biology, Chartered Biologist, 1991-present
Member of the Forensic Science Society, 1985 -1995
Member of the American Heart Association, Council for High Blood Pressure Research, 1993-1996
Member of the American Association of Pharmaceutical Scientists, 1994-1999
Member of the American Association of Colleges of Pharmacy, 1994-1998
Fellow of the American Heart Association, Council for High Blood Pressure Research, 1996 present
AWARDS
The Carnegie Trust for the Universities of Scotland Tuition Award, Edinburgh, Scotland, 1985-86.
Forensic Science Society Bursary Award, Forensic Science Society, Harrogate, England, 1991.
Merck Travel Award, 47th Annual Fall Conference of the Council for High Blood Pressure Research, San Francisco, CA, 1993.
Hypertension Summer School Travel Award, German Institute of High Blood Pressure Research, Ross Priory, Scotland, 1993.
American Heart Association, Florida Affiliate, Postdoctoral Fellowship, 1993-94
American Heart Association, Florida Affiliate, Postdoctoral Fellowship, 1994-95
FUNDED RESEARCH
The National Institute of Justice, Washington DC, $86,500, Co-Investigator.
The use of Microcrystal Tests with Fourier Transform Infra-Red Spectrometry for the Rapid Identification of Illicit Cocaine, 1990.
American Heart Association (Florida Affiliate), Tampa, FL, $270,000, PI.
The Role of Angiotensinogen in Hypertension and its subsequent Inhibition by Antisense Oligodeoxynucleotide Technology, 1995-1998.
National Institute of Health, Washington DC. $4,131,233, Co-Investigator.
Discovery for Novel drugs in Alzheimers Disease, 1996-2001.
American Heart Association (FA Grant-in -Aid), $99,966, Consultant.
Renal Transport of Dopamine In Hypertension, 1997-1999.
United States Department of Agriculture, Washington DC. Co-Principle Investigator.
Function of an Estrogen Induced Secreted Oviduct Protein, $220,000, 1997-2000.
UNIVERSITY SERVICE
Member of the Student Conduct Committee, University of Florida, 1997-98
Member of the Academic Performance Committee, College of Pharmacy, UF, 1996-97
NON UNIVERSITY SERVICE
Member of Drug Evaluation Panel, Current Drugs Ltd. London, UK., 1997- 1999
Research Peer Review Committee, American Heart Association, Florida Affiliate, 1996-99
Member of the Progress Review Sub-committee, American Heart Association, Florida Affiliate, 1997
Moderator, Annual meeting. Association of American Pharmaceutical Scientists San Diego, CA., 1994.
Editorial Review Board, Regulatory Peptides, 1995
Organizational Committee, Association of American Pharmaceutical Scientists, SE Regional Meeting, Morrisville (RTP), North Carolina, 1996
Drug Chemistry seminars - Office of the Public Defender, Chicago, IL., 1988-92
Presented training seminars for crime scene investigators, FDA and attorneys, 1988-92
PUBLICATIONS
D Wielbo, IR Tebbett, C Fitzsimmons and S Palenik. The use of FTIR and microcrystal tests for the detection of cocaine in street drugs. Microgram, 23:11, 258-264, 1990.
D Wielbo, IR Tebbett. The use of microcrystal tests in conjunction with Fourier transform infra-red spectroscopy for the rapid identification of street drugs. Journal of Forensic Sciences, 37, 1134-1148, 1992.
AK Larsen and D Wielbo. Gas chromatography and forensic drug analysis, in Gas Chromatography In Forensic Science, Ellis Horwood, Chichester, England, 1992.
D Wielbo, IR Tebbett. The use of micro-FTIR for the rapid identification of street drugs: determination of interference by common diluents. Journal of the Forensic Science Society, 33(1), 25-32, 1993.
D Wielbo, R Bhat, G Chari, IR Tebbett, A Gulati and D Vidyasagar. HPLC determination of morphine and its metabolites in plasma using diode array detection. J. Chromatography, 615, 164-168, 1993.
R Gyurko, D Wielbo and MI Phillips. Reduction of blood pressure by antisense to AT1 receptor mRNA and angiotensinogen mRNA in the brain of SHR rats. Regulatory Peptides, 49:167-174, 1993.
H Meng, D Wielbo, R Gyurko and MI Phillips. Antisense inhibition of angiotensin type 1 receptor expression on drinking and vasopressin responses to central angiotensin in Sprague-Dawley and spontaneously hypertensive rats. Regulatory Peptides, 54:543-551, 1994.
MI Phillips, D Wielbo and R Gyurko. Antisense inhibition of hypertension: A new strategy for renin-angiotensin candidate genes. Kidney International, 46:1554-1556, 1994.
D Wielbo, C Sernia and MI Phillips. The distribution and antihypertensive effects of phosphorothioated antisense oligodeoxynucleotides in SHR. Hypertension, 25:314-319, 1995.
V Srinivasan, D Wielbo, K Sloan, B Freiburger, J Karlix, J Simpkins and IR Tebbett. Analgesic and immunomodulatory effects of codeine and codeine-6-glucuronide. Pharm Res, 13(2):296-300, 1996.
D Wielbo, A Simon, MI Phillips and SM Toffolo. Inhibition of hypertension by peripheral administration of antisense oligodeoxynucleotides. Hypertension, 28:147-151, 1996.
S Al-Suwayeh, GA Brazeau, D Wielbo and IR Tebbett. In vitro-in vivo myotoxicity of loxapine liposomes following intramuscular injection. Pharm Res, 13:9, 1385-1388, 1996.
D Wielbo, N Shi and C Sernia. Antisense inhibition of angiotensinogen in hepatoma cell culture. Biochemical Biophysical Research Communications, 232:3,794-799, 1997.
D Wielbo. Drug Evaluation: MK-996 (Merck & Co Inc). The Investigational Drugs Database, August 25, 1997.
D Wielbo. Drug Evaluation: Sch-42495 (Schering-Plough Corp). The Investigational Drugs Database, August 25, 1997.
D Wielbo. Future needs and developments in antisense technology: Meeting News. Investigational Drugs Weekly Highlights, 42:30-33, 1997.
V Srinivasan, D Wielbo and IR Tebbett. Analgesic effects of codeine-6-glucuronide after intravenous administration. European Journal of Pain, 1:185-190, 1997.
J Peris, BJ Jung, A Resnick, P Walker, O Malakhova, Y Bokrand and D Wielbo. Antisense inhibiton of striatal GABAa receptor proteins decreases GABA-stimulated chloride uptake and increases cocaine sensitivity in rats. Mol Brain Research, 57:310-312, 1998.
F van Haaren, R de Jongh, JB Hoy, JL Karlix, C Schmidt, IR Tebbett and D Wielbo. The effects of acute and repeated administration of pyridostigmine bromide on response acquisition with immediate and delayed reinforcement. Pharmacol. Biochem. Behav., 62(2):389-394, 1999.
J Hoy, BA Cody, JL Karlix, CJ Schmidt, IR Tebbett, S Toffolo, F van Haaren and D Wielbo. Pyridostigmine bromide alters locomotion and thigmotaxis of rats: Gender effects. Pharmacol Biochem Behav, 63(3):401-6, 1999.
Van Haaren, F., Cody, B., Hoy, J.B., Karlix, J. L., Schmidt, C., Tebbett, I. R., & Wielbo, D. The effects of pyridostigmine bromide and permethrin alone, or in combination, on response acquisition in male and female rats. Pharmacology Biochemistry and Behavior, 66, 739-746, 2000.
D Wielbo. History: (a) Forensic Sciences. Encyclopedia of Forensic Sciences, Academic Press (2000)
D Wielbo, K L Lothridge. Forensics. Encyclopedia of Information Systems. Academic Press (2002)
K Savage, D Wielbo. Pharmacology of Illicit and Licit Drugs. Encyclopedia of Forensic Science. Elsevier Press, in Press.
