Research Interests
Peptide Chemistry, Medicinal Chemistry, G-protein Coupled Receptor (GPCR) Pharmacology, Human Receptor Polymorphisms, Neuroscience, Voluntary Exercise of Mice, Obesity, Diabetes, and Feeding Behavior.
Our laboratory focuses on the understanding of peptide hormone endocrine systems in the brain, and their involvement in feeding behavior, exercise, diabetes, and obesity. We utilize multidisciplinary approaches including chemistry, chemical biology, biochemistry, molecular biology, pharmacology, physiology, and neuroscience to study endocrine systems. The techniques we use to answer different research questions include combinatorial chemistry, peptide design and synthesis, receptor pharmacology and compound analysis, computer assisted molecular modeling (CAMM), NMR spectroscopy, receptor mutagenesis and pharmacology, use of knock-out and transgenic mice, qRT-PCR, immunohistochemistry (protein expression in the brain), in situ hybridization (mRNA expression in the brain), and administration of compounds into mice.
We are always looking for talented, highly motivated, and productive undergraduate students, potential Ph.D. graduate students, and postdoctoral fellows. Please email CV and inquires about currently available positions.
Recent Publications
pubmed: carrie haskell-lueva...
NCBI: db=pubmed; Term=carrie haskell-luevano, Florida